The 2016 Colorado received four stars in the front crash test, five stars in the side crash test and three stars in the rollover crash test.
The rating applies to rear-wheel-drive and four-wheel-drive versions of the Colorado.
Five stars is the highest rating.
The 2016 Colorado, a carryover vehicle, is expected to arrive at Chevrolet dealerships this summer.
Standard safety equipment includes six airbags, electronic stability control with rollover mitigation technology, trailer sway control and hill start assist. Hill descent control is standard on the Z71 model.
A safety package is optional on Colorado LT models and includes forward-collision alert and lane-departure warning systems.
The Insurance Institute for Highway Safety has not rated the 2016 Colorado.
Edmunds says: Truck buyers keeping score will note that the 2016 GMC Canyon also earned a four-star overall safety rating from NHTSA. The 2016 Nissan Frontier and Toyota Tacoma have not been rated.