On sale now at Cadillac dealerships, the 2016 CTS received five stars in the front, side and rollover crash tests.
The rating applies to rear-wheel-drive and all-wheel-drive versions of the CTS.
The new 2016 Cadillac CTS-V high-performance sedan has not been rated.
Standard safety equipment on the 2016 CTS includes 10 airbags, a rearview camera, electronic stability control with traction control and antilock brakes.
The Driver Awareness package is standard with Luxury, Performance and Premium Collections, as well as V-Sport. It includes side blind-zone alert, lane-change alert, lane-keep assist, lane-departure warning, forward-collision alert, rear cross-traffic alert and a Safety Alert seat.
The Insurance Institute for Highway Safety has not rated the 2016 CTS.
Edmunds says: Safety-minded car shoppers should note that the 2016 Audi A6 and BMW 5 Series also earned the highest five-star safety rating from NHTSA. The 2016 Mercedes-Benz E-Class sedan earned a four-star overall safety rating.