It is priced at $131,895, including a $995 destination charge.
Just 50 units of the special hot-rod sedan will be available to U.S. shoppers.
The Pure Metal Silver finish, which is designed to create a light-dark effect, is at the heart of this limited-edition model. BMW said it is the most exclusive paint treatment available by BMW Individual.
The car gets a Glacier Silver Metal base coat, followed by the application of Pure Metal Silver.
Other details include 20-inch M light alloy wheels, an M Performance Exhaust with carbon bezel and black M Performance kidney grille.
The cabin features Merino leather with contrast stitching, along with aluminum trim.
The 4.4-liter twin-turbocharged V8 in the Pure Metal Silver Limited Edition has been tweaked to produce 600 horsepower, an increase of 40 hp compared to the standard model. Torque increases by 16 pound-feet to 516 over the standard M5.
The engine is linked to a seven-speed M dual-clutch transmission.
The car is outfitted with a standard Competition package, which includes a 0.4-inch lower ride height, stiffer suspension and firmer stabilizer bars.
Other standard equipment includes M carbon-ceramic brakes. An M Driver's package boosts the vehicle's top speed from 155 mph to 190 mph.
BMW also throws in a one-day high-performance driving school at one of the two BMW Performance Centers in the U.S.
The key rival to the BMW M5 is the Mercedes-Benz E63 AMG.
Edmunds says: It's time to get the conversation going with your BMW dealer if you want to get your hands on this highly desirable M5.