I replaced my 1991 Previa (Toyota) which had 214000 miles with the 2005 Sienna XLE Limited AWD which has the navigation system. This is a must. It can get you to and from anywhere. I have been able to navigate in, out and around Washington DC, Philadelphia, etc., not knowing where I was going. It paid for itself within 4 weeks of having the van. It has a wonderful drive.
Navigation system; DVD player when kids are aboard; seats are very comfortable and adjustable lumbar support is great in the drivers seat.
I think with vans in general when you are looking back to your right side to view traffic it is not always easy.