We purchased a Toyota Highlander the last week of June, 2006. We got the base model with the 2.4L 4-cyl. engine, which has very good performance. We have no problems with highway driving or acceleration. I haven't owned it long enough to give hard mileage estimates, but it looks like the 22/27 or so on the sticker is accurate with 87 octane. The backseat is VERY roomy. The ride is terrific when compared to other SUVs in this segment, being based on the Camry. There's no 'rollover' feeling at all when changing lanes at highway speeds. The turning radius is incredibly small for its size. Being based on a Camry, I expect to own this car for at least 150,000 miles.
ROOMY backseat, soft ride, comfortable for ALL seats - not just the driver, 4-cylinder available and has good performance and mileage, under-floor storage in back, tight turning radius, full-size spare, based on Camry so drivetrain and suspension should be rock-solid, quiet on the road.
Need more cupholders up front. Get rid of the split-gauge cluster, instead make the face smooth all the way across. Because the gauges are set into the dash, the split makes it hard for light to get in, thus it's hard to read the gauges in the daytime because they are set back. Nighttime is fine.