I have a 2001 SE 4x4.
Bought it in 2005 with 64,000 miles.
5 years later and now over 175,000 miles on it, we've had no engine or transmission issues with it.
I did have to replace an electrical component in the a/c this summer for about $250 but otherwise it's just been routine maintenance.
It's a fun truck to drive and very reliable.
Not the best backseat for carseats but it is manageable.
We're in the process of selling it only because our 3rd child is on the way and we can't fit the family in this car anymore.
But that is the only reason we're selling!
It's been a great car.