We've owned our Murano for 6 years now and have had quite a few problems. The alternator failed at about 20k, one of the speakers has cut out randomly since about 40k, and I have gone through many sets of tires since I bought the car. I now have 100k on this vehicle and it has been in the shop more times then I would have liked. Fuel economy is unimpressive at 17-18 city and low 20s on the highway. I recently had the timing belt and front wheel bearings replaced. Noticed a burning smell inside and Nissan dealer said everything's fine. Probably won't be buying another car from Nissan.
Exterior and interior are both pleasing to look at. The Bose 6-CD changer is nice. Comfortable and roomy. Xenon headlights are very useful. CVT is pretty nice as well.
Better reliability and fuel economy. Sun visors that stay up would be nice as well.