I purchased a Toyota Highlander for my wife a few years back and felt the only new car for me was Toyota. I was so close to buying the Camry Hybrid but after reading reviews here, I tested the Altima. Sold! Im a big guy at 64 230 lbs and the comfort in the Altima is far superior to the Camry. Gas mileage is great at 38. And I think it looks much better than the Camry.
Hybrid drive of course, gas mileage, car looks, and the little plastic pull-out thingie on the sun visor to block sun from side windows.
Little more flexibility with packages. Forced to get leather seats if you want the Nav system.