I have owned 2 Mercedes cars in the past and by far the new S-class is the best car this company has put out. Everything in this car screams luxury and perfection. The ride is super smooth and even as the driver you feel like you're being chauffeured. The cabin is extremely quiet and the interior is designed to be elegant and clutter-free. The computer console is very intuitive and much more user-friendly than BMW's system. I've only owned the car for a week, so I can not say much about the reliability. But from what I have read, Mercedes has stepped up their game and this new generation of the S-class is supposed to be very well built. I own the s550 4matic an get about 16mpg in the city.
Interior and exterior design. Large amount of legroom both front and back. Easy to use computer system. The AMG appearance package really gives the car a killer look.
Lots of options are only added as part of upgrade packages. At this price-point, things like rear seat temperature controls should come standard. If you are in the market for this car, make sure to add at least the Premium 2 package. The side mirrors are a bit small.