The LWB S320 is my second Mercedes (replacing a 300E) and I hate to even consider trading it off. It is smooth, quiet although not a rocket off the line, it will hit highway speeds of 125 plus without issue. I hit and totaled a U-Haul truck that ran a red light several years ago and the Mercedes kept me safe and sound. The car was repaired and continues to be a great daily driver. I highly recommend buying and keeping a well maintained Big Body Benz. My wife enjoys driving the S320 as much as her Lexus especially on longer trips. I'm nearly 6'6" and I can tell you this is a great choice for a tall person wanting something besides an SUV or truck.
Great comfort and standard features. Excellent mileage; 18 city and 24 highway consistently. Super safe and very quiet. Lastly every one has excellent leg room.