This is our 3rd MB. The wife didn't want a minivan, and our ML was out growing our family. We got a great deal, $12000 off sticker! The R350 was the perfect choice for our family. It's large enough to fit 6 very comfortably and it's very luxurious. It's a large vehicle but it drives like a sedan. I've got a sports sedan and I even enjoy driving the R350. The NAVI is not as user friendly as the Japanese built cars but we are slowly getting used to it. We love the HK stereo and the panoramic roof. The wife appreciates the auto tailgate. The rear doors are a little too big at tight parking spaces. No regrets at all!
HK stereo, panoramic roof, handling, and comfort/luxury.
Standard parktronic since it's hard to see where the nose and the rear of the car is. Standard roof rack and smaller rear doors. Better gas mileage; yeah, it's a 7 speed and it's heavy for safety reasons, but MB engineers can do better.