I've owned Mercedes E-class wagons since my first purchase back in 2000 when a bought an E320 wagon. That car was great, then I purchased a 2004 E320 wagon, better but not excellent, then came my E350 4MATIC. It has so many options to choose from that the tested price went from a 55k MSRP to a 66,000 dollar family mover. It has a much more powerful engine and handles much better too. Also it offers equal amounts of gas mileage although it weighs more and has a more powerful engine. It has 270 hp and is all this 2 ton car needs to reach 60 mph in 7 seconds. Has the same horsepower as my wife's Lexus ES350 yet weighs 550 lbs more and still has the same acceleration times. Very great car!
Distronic is cool although seems pretty useless unless you pay zero attention to the road ahead of you. The COMAND navigation is great and not as complicated as most poeple have claimed. Heated and ventilated seats are cool and the 4MATIC works great in New York's winter conditions and on rainy days
3.5L V6 produces 268 hp which is about average for this displacement, but many cars with 3.5L V6's from Acura, Infinti, lexus, and BMW produce up around 300hp. 7.2 sec to 60 mph is what i timed and is pretty quick for a 4,250 lb wagon, although its almost a full second slower than the sedan version.