After much research and driving most competing models, including BMW 5 series, Lexus LS 400, Mercedes e320, etc. the e430 proved to be the car for me. 30+ mpg hwy at 75 - 80 mph. Quiet, comfortable, most E320 options are standard. This car feels soft but as soon as you push it a bit in hunker's down and handles! Great stereo and seats! Find a reputable independent shop and maintain it well. Find a well maintained carfax certified model. It'll never be as care free as a Camry, but it will never drive like one either!
Stereo, seats, power, mpg if driven gently. Classic looks also.
Conservative look may not appeal to some, but doesn't stand out to the highway patrol either!