I traded in my 2007 RX350 for this hybrid and have been quite pleased.
It feels much more stable on the road.
The navigation is disk based and is somewhat different, as it trades the touchscreen for a mouse-like control on the console.
I miss the storage compartments in the back that are now taken by batteries.
I expected higher MPG and would probably get it if driving stop-n-go on city streets, however Dallas driving uses lots of highways.
It has good power, but I find myself starting slower, trying to reach the stated MPG.
I initially used Premium fuel, then switched to Regular - noticed no difference in performance or MPG.
Quiet, powerful, comfortable, plenty of room, "solid" feel on the road.
Good connectivity to media players via USB and bluetooth.
Put guidelines on backup camera - like on Infinity.
I miss the holder for sunglasses in the roof console.
Use more power from batteries and use smaller engine - especially at low speeds.