Drove the MB M class and Acura MDX and settled on the Lexus. Acura has superior nav system...the delay after every verbal command from the Lexus nav is extremely annoying and time consuming, but great for folks who have trouble mastering the nav I guess. Had a major rattle within the first week, very disappointing at this price. Quiet secure ride but no one could ever call it a "fun" drive.
Climate controlled seats (specifically the cooling function), mouse for controlling major functions has click style feedback like your computer mouse. Vastly improved rear backup camera. Comfortable seats.
Tiny and oddly placed digital clock. Gas consumption screen is next to useless and needs to numerically calculate mpg not show graphs, very difficult to use plug in jacks, have to dig through console to use. Desperately need lights on garage door opener buttons!