If you're looking at the RX 350, then I don't need to tell you about reliability, fit and finish, etc. I picked up my 2009 w/nav a few weeks ago and I'm coming from a 2000 RX 300. Prior to that I've owned about 15 other vehicles - Toyota, Honda, Nissan. I drove the FX and the feel was much more sporty. However, the trunk space sacrifice was unacceptable. I've driven the 2004-2006 and I wasn't convinced that the improvements to my 2000 were worth the premium. However, in 2009, I can say that they are.