I am on the road a lot and appreciate how quiet this vehicle really is. The cabin is so quiet I actually look forward to talking on the cell phone over the car's blue tooth. I have owned Hondas and Toyotas in the past so appreciate the level of build quality that went into the RX. I have near 15k and not one single problem. I average around 21 in the city, 27 on the highway. In summary, Lexus RX 350 is the gold standard of SUVs.
Quietness, quality of interior materials, and navigation/blue tooth system. The integrated blue tooth with navigation is an outstanding feature, can't live without it.
Replace center console with fixed console and emergency brake handle - get rid of the floor mounted emergency brake pedal.
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