This is basically a Toyota Highlander with upgraded trim, equipment and dealer network. That said, you give up some space for much better ergonomics, a little more style (although neither vehicle is going to win any one-off design awards) and gizmos. Reliability is Toyota all the way, but with a service department that is told to treat you like a valued customer instead of joe schmo. Performance is in the range of a Camry (same chassis, not surprising) which is to say it gets you to Target and back but you're not going to be autoXing this thing. Despite the supposed exclusivity of Lexus, the RX sells well so you see a ton.
We bought a 2006 RX 330 in November, the mileage is over 3000 and we only went to the dealer for a oil change. Nothing is wrong and the comfort is great. The front seats can lay back flat and the back seats can recline to. There is a back up camera and sensors. There are I believe eight airbags but I did not fully count it. The GPS is great but sometimes will lose its accuracy. Very very reliable. I am waiting for the 2009 Lexus RX 350.