I bought the car three years ago w/ 80k. I now have a bit over 140. Absolutely no problems whatsoever. I did the 90k maintenance which was about $1000, but was very extensive. The car is comfortable, quick, and surprisingly economical. Every once in a while I get the itch to buy a new car, but think what could I replace this with that would come close. The answer is nothing. I have two other Lexus's that I bought used, a '92 SC300, and a '95 ES 300 and have been just as fortunate with those.
My daughter now has the ES at college with 260k, and my SC is my weekend car with 180k.