I just bought my IS250 1 week ago and so far it's been great! I have heard some complaints on how the initial pick up is lagging some, but I have yet to feel inadequate upon "take off". It's a smooth ride and really fun to drive. The navigation system takes a little getting used to-- it's really just a matter of getting the lingo down. I have the tan interior, which tends to get dirty rather quickly, but the perma-plate guard that they put on seems to be keeping the dirt off. The only thing I can complain about is the slightly small back seat (but hey, i'm not sitting in the back!!)and the blind spots. Other than that, I love it!
AC ventilated seats, keyless entry/start up, and good looks!