I have driven my 2006 Lexus IS 250 for 40,100 miles. I purchased the vehicle new in 2005. The computer indicates the average gas mileage for 40,100 miles is 26.1 miles per gallon. Highway gas mileage is as high as 36 mpg when driving 65 mph. I have been using mid grade gasoline and the mileage and performance is the same as premium grade. I back off the accelerator when possible to increase the gas mileage. The car has the original brakes and tires. The front brakes need to be replaced but the tires still have at least 10,000 miles left on them. The car has been extremely reliable since a few initial glitches. No major repairs to anything.
The gas mileage is great if driven properly. I use the paddle shifters to down shift when slowing to save the brakes. The car is extremely reliable and comfortable. The OEM tires will probably last 50,000 miles. This car is the best Lexus for the money.
Lexus dealers are now offering an after market back up camera incorporated into the rear license plate frame for $600.00. The blind spot when backing up is an annoying weakness. What about a hybrid version?