I bought it at 94,000 in 2009 and I've driven it for a year now for both local driving and couple of road trips. It is an excellent car for all purpose and is incredibly comfortable. Brakes are something to get used to and the gas mileage isn't great. I've taken it to Lexus dealer for maintenance every 5,000 miles (which is quite costly) and I haven't had to do anything else. I'm definitely hooked on Lexus now.
Comfortable ride. Great sound system. Overall, very well built.
Gas mileage is an issue. But given its comfort and acceleration, I'm willing to live with 17-22 MPG.