This is my second Lexus; traded in my 2001 ES 300, which I also loved. But this is a totally different car; plush, powerful, yet still quiet and reliable. I'm impressed with the fit and finish of the dash and controls, and love the Bluetooth compatibility. This may just be my all-time favorite car (except for the '66 MGB that drove me to the poorhouse when I was young). Plenty of power, yet smooth as silk.
Never thought I'd say this, but the dual A/C controls have solved my lifelong battle with my wife over climate control (even if it's just a psychological difference, it makes her happy).
The rear window is a bit narrow, but so far I don't notice a significant visibility problem. Cup holders are improved over 2001, but could be a bit deeper.