Drove confidently from NV to IL with just under 199K purring like a kitten (and still purrs). Had to replace front struts and control arms, that's about it. Went through over 3 dozen new and used cars (BMW, Acura, Honda, Toyota, Nissan, Mitsubishi, GM, Dodge, Mazda, VW, Saab), but none, NONE like the ES300. This is car is ultra reliable and it can probably go for another 100K. This is really why many are loyal to the Toyota/Lexus brand. It's hard to beat it's quality and reliability combination. The engine will most often outlast the body and suspension. If there is a need for used car, this is the best one to get.
Engine is still smooth and sound. Granted it's a more refined engine, but being a '98 and 200K, it's quieter than my '07 V6 RAV4. Paint still glossy after 10 years. Parts are always available, if needed. No wonder these cars have great resale value.