I traded my 06 Accord in for a Pilot because of space issues after having our first child. I love my Pilot! The space in the back is amazing (with the back seat laid down). The drive is awesome. My husband keeps saying he can not believe how well it drives. The gas mileage is a bit disappointing but we realized that it would drop drastically from my Accord. we are averaging around 17-18 mpg. One complaint is the fog light inserts. Because of the base model, the just put some plastic caps in them. Not too attractive. And the rear ac/heat controls are only in the back of the middle console, so you can't see them from the front seat to change.
Drive, space, console, dash.
Make the rear a/c controls also in the front, make fog lights standard.
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