I've had my new Odyssey for a month and am very satisfied.
I find the 5 speed transmission very smooth and would not recommend spending an additional $4000 just to obtain a 6 speed and another 1 MPG.
I averaged 17.8 MPG on my first tank of gas per the on board computer (17.86 based on actual fuel consumption).
This was with 100% A/C and city driving.
I miss the middle row Stow and Go of my former Grand Caravan, but this is a small price to pay given the quality of this vehicle.
The electronics, the quietness and smoothness of the ride, and the rear-view camera.
The head rests of the middle row of seating partially block the rear view.
I deal with this by lowering the seat backs.
The obvious remedy is to have retractable head rests.