My wife had gone on record as saying she would never drive a minivan. Three kids later she's driving the Odyssey and loves it. The interior is extremely versatile and great room for the kids, their friends and all of the accumulated stuff. We've had it on several trips and it's performed great with just over 25 mpg on the highway and around 19-20 around town. The seats are comfortable and it drives more like a car than most vans and handles surprisingly well. It does have a lot of wind noise, primarily from the front passengers seat, but we just turn the radio up. The breaks are softer than what I'd prefer but not to the point of feeling like we're in danger. My wife's glad we bought it.
Adaptability of seating, handling of vehicle, ride comfort, storage space especially in floor storage, VCM makes gas mileage livable.
Do something about the road and wind noise, improve the breaks, and since we're wishing it would be nice to have the option of a hybrid, especially for in town driving,