We bought our '05 Odyssey 4 years ago and have since logged a little over 80,000 miles with it. We love it! I've always said not to buy the first year of a new model, and there have been issues, like having to replace the front brakes in the first 10,000 miles, and a few recalls, but over all, I'm glad we bought this van. It has sufficient power, handles great, and looks good too! I noticed on another review about the need to replace a noisy power steering pump, which I'll have to do as well, because of the noise it makes. Overall, there have been a few minor issues, but I would still get another one. My advice would be to get the extended warranty like we did on a first year model.
Comfort, handling, power.
Figure something out with the brakes and steering pump.