So far, so good. The CR-V definitely leads the small SUV class in terms of refinement and build quality. No question there. As noted elsewhere (everywhere?), the low-end power (torque) is lacking on the CR-V; however, once you're at cruising speed the power is adequate for normal, safe, efficient driving maneuvers. The only thing that would have made me second guess the purchase is if I lived in a hilly or mountainous region--those are the times when you can really feel/hear the 4 cylinder working hard to propel the vehicle's substantial weight. Otherwise, the CR-V is a pleasure to drive. It feels nimble, reliable, and inspires a feeling of safety on the road.
Build quality is excellent inside and out, interior design is unparalleled in the class, front seats are comfortable for the long haul (but might be a bit of a squeeze for a fatty).
Increased low-end power, better stereo, and more MPG would all be nice.