I have a 1999 CR-V EX with 206,000 miles and and its still going strong. As others have said, adjust the valves every 20K - 30K (or sooner since its so simple to do in less than an hour without much knowledge at all), change your fluids as scheduled (Transmission, motor oil, rear diff oil, etc.) and it will last a long, long time. Even the cloth interors on these cars lasts forever without showing wear. The vehicle is amazingly roomy inside.
AWD, gas mileage, roominess for a smaller vehicle.