Transmission problems! Transmission replaced at 110,000 miles and again at 165,000 miles. I have done the regularly scheduled maintenance on this car. I don't think it's my driving style either. For example, I usually get at least 60,000 miles from a set of tires (on third set). Honda replaced first transmission for me without any charge (or any explanation). Second one cost me $2k. Family has owned hondas since 1981. I have enjoyed owning this one for 9 years. Not sure if I will buy another Accord. I have not seen shining reviews of the 07 - 09 models.
V6 engine. Car interior still looks good after all these years.