Bought this thing with around 45K miles on it in 2004 and drove it until some kid parked his Blazer in my trunk last week at 127K miles. Great car. Not the most fun car I've ever driven, but still not bad. No issues other than the cheap factory GM alternator had to be replaced at around 50K miles which I was expecting. No tranny issues. Driver's side leather seat started looking rough but not bad considering it was a 10 year old car. All in all no complaints other than the alternator and maybe a tighter, sportier suspension. Super reliable, what you can expect from a Honda.
Seats are pretty comfortable. Plenty of leg room for me (6'2"). The 3.0 VTEC has plenty of juice without sacrificing gas mileage (got about 28 mpg on hwy). Reliable, probably could have gotten 200K miles out of it if it weren't for that stupid kid.
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