My 98 Ford F-150 2WD regular cab manual V6 has been a true champ. I have almost 150,000 miles on it and it is still running strong. This was the first truck that I bought new and was worth every penny. Unfortunately with two little ones, I have to let 'ole blue go. I'm going with another Ford though (06 Crew Cab). This was one tough and special truck!
Reliability. I have replaced the alternator (easy to do myself!) and have had a front tie rod replaced. Other than that nothing other than regular stuff!