I've owned 11 vehicles in my life, most of them purchased new, and I can honestly say this is the happiest I've ever been overall with a vehicle. The list of issues I've had with this truck is short - I had a leaking coolant hose which I fixed with a 75 cent hose clamp. That's it in over 36K miles. I'm averaging 17.5 mpg (hand calculated) over the life of the truck. It tows well, can accomodate 5 people decently (though not for extra long trips), and is fairly comfortable. I intend to keep this a long time, unless the new 6.7 Cummins with the 6 spd. automatic tranny is just too good to pass up. I'd buy another one in a heartbeat. Oh - I also got this $5K below a comparable Ford.
Ensure injector and lift pump reliability. I haven't had any problems with either, and there have been improvements in the 05 and 06 models. But these are the most reliable diesels out there - why not fix these issues and make them bulletproof?