I bought my Neon new in 1998 and have had only one major issue and that was with the defective head gasket. Other than general maintenance, it has been a great car. I just put a set of 75000 mile tires on it and I talked to my mechanic and he said it should hit 400,000 with no trouble.
Have always used Catrol Syntec and I get about 30-35 in town and around 40 on the highway. I have had a few trips (recently) where I hit 45-48 mpg.
Other minor issues include the leak around the driver's side tail light and my sunroof motor went out.
Could not have spent $17,600 any better way.