2001 Chevrolet S-10 4dr Crew Cab LS 4WD SB (4.3L 6cyl 4A)
I purchased my S10 4x4 Crew Cab with 25K, and now have over 80K. One repair in that entire time - front ball joints. Now, I did not keep them greased, so I cannot entirely blame Chevy, although I understand these are a weak point. Other than that, no problems at all.
Durable, reasonable fuel economy vs. power, 4x4 takes me through anything (18" of snow didn't even make it work hard), good power for trailer work. Decent ride, especially considering it's a 4x4 truck. Easy to perform maintenance (fluids, brakes, etc).