I bought this truck about a year and a half ago with 100,000k on it but I've owned an S-series vehicle before, so the mileage didn't bother me. I've driven it almost 40,000 miles so far and I really don't have any complaints. I only had to replace the MAF sensor and heater core, and I've done everything from auto-crossing to drag racing with it. I've put it through its paces thousands of times and it hasn't given up on me yet. It is definitely a truck that is decently easy to work on if something goes wrong. I've averaged around 20-21 mpg driving 50% city/highway. It's decent for a v6 truck.
Xtreme came with the "ZQ8" suspension, which is stiffer and it handles great. I like the quick ratio steering box, hop shock in the rear, and ability to take a beating.
I'd be nice to have some better seat levers, and a little more economical engine as far as gas mileage goes. And all S10 models should come standard with a limited slip differential, it'd help immensely in the snow.