We looked at the usual suspects in this category. Ultimately, we went with the MDX as the best overall combination of drive quality, convenience and comfort - it's a great car.
Very good power, nice handling, and very quiet on the road. Tons of safety features. Stereo has great sound in the Touring. Interior looks great w/ebony leather (shame they use fake wood). 3rd row easy to fold/unfold and allows for tons of cargo space (when down).
Real wood on dash! Daytime running lights. Laser cruise control like on the Lexus. You have to pay extra for a cargo cover (lame).